Zebrafish Cardiotoxicity Multiomics Data for Bioactive Peptide BP1

151.0 KB of transcriptomic and metabolomic data from a zebrafish model investigating the cardioprotective effects of a novel bioactive peptide, BP1. The dataset, uploaded by Shweta Thakur to figshare in April 2026, contains results from experiments on isoproterenol- and doxorubicin-induced cardiac damage. Analysis includes cardiac morphology, functional parameters, and untargeted metabolomics.

Use Cases

• Identify gene expression changes associated with cardiotoxicity based on transcriptomic data mentioned in the description
• Analyze metabolic pathway alterations (e.g., sphingolipid, glutathione metabolism) based on untargeted metabolomics results
• Validate cardioprotective effects of bioactive peptides based on cardiac morphology and functional parameter data
• Perform weighted gene co-expression network analysis (WGCNA) based on the transcriptomic data

Strengths

• Data integrates transcriptomic and metabolomic profiles for a multiomics perspective
• Experiments were conducted on both zebrafish larvae and adult models
• Dataset is licensed under CC-BY-NC-4.0 for clear reuse terms

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The 151.0 KB file size suggests a limited scope of data

Provenance

Source

figshare

Collection Method

Experimental data from zebrafish models treated with isoproterenol and doxorubicin, followed by transcriptomic and metabolomic analysis.

Time Range

Experimental timeframe not specified; dataset uploaded in 2026.

Freshness

Last updated 2026-04-14 17:43:33; freshness should be verified

Geography

null