Supplemental Data on Muscle Glycogen Dysregulation in Critical Illness

Supplemental data from a randomized controlled trial investigating skeletal muscle metabolism in critically ill patients. The dataset likely contains measurements of mitochondrial function, ATP, glycogen, lactate, and gene expression from patients during and up to 6 months after ICU admission, compared to elective surgery and muscle disuse control groups. The data was published by Tom S.O. Jameson in 2026 to accompany a study in the American Journal of Physiology-Endocrinology and Metabolism.

Use Cases

• Analyzing temporal changes in muscle ATP and glycogen levels based on measurements taken at ICU admission, day 7, and 6 months post-admission.
• Comparing gene expression related to glycogen metabolism between critically ill patients and control groups mentioned in the description.
• Investigating associations between metabolic markers like ATP content and ICU-acquired weakness (ICUAW) based on the reported statistical trends.
• Modeling the impact of functional electrical stimulation-assisted cycle ergometry (FESCE) on muscle mitochondrial respirometry as described in the trial.

Strengths

• Data is derived from a randomized controlled trial with a nested sub-group, a design mentioned in the description.
• Includes longitudinal measurements from ICU admission up to 6 months post-discharge, providing a time-series perspective.
• Published under a permissive CC-BY-4.0 license, facilitating reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (358.9 KB), indicating limited scope or summary-level data.

Provenance

Source

figshare

Collection Method

Collected via a randomized controlled trial of functional electrical stimulation-assisted cycle ergometry (FESCE) vs. standard care in critically ill patients.

Time Range

Measurements taken during ICU stay and up to 6 months post ICU admission.

Freshness

Last updated 2026-04-27 12:34:34; freshness should be verified.

Geography

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