MWM-raw: Microscopy Data from Alzheimer's Nanoparticle Treatment Study

1.2 GB of TIF and AVI files containing raw microscopy data from a study on chiral cobalt hydroxide nanoparticles for Alzheimer's disease treatment. The dataset, authored by jingru shi and last updated in May 2026, captures in vivo experimental results from 3xTg AD mice, showing reductions in amyloid-β and phosphorylated tau levels. It was released under a CC-BY-4.0 license on figshare.

Use Cases

• Analyze changes in neuronal synaptic integrity based on microscopy images mentioned in the description
• Study microglial and astrocytic activation patterns from the provided image data
• Investigate nanoparticle accumulation in liver macrophages using the video or image files
• Validate image-based biomarkers for amyloid-β and phosphorylated tau reduction

Strengths

• Dataset size is 1.2 GB, indicating a substantial volume of raw image and video data.
• Specific experimental outcomes are described, including a 69.74% reduction in amyloid-β and a 78.38% reduction in phosphorylated tau.
• Data is associated with a detailed mechanistic study published on an academic repository (figshare).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.
• The description focuses on experimental results, not on the structure or annotation of the raw data files themselves.

Provenance

Source

figshare

Collection Method

Likely contains raw microscopy data (TIF, AVI files) generated from in vivo experiments on 3xTg AD mice.

Freshness

Last updated 2026-05-09 08:58:45; freshness should be verified.