Myeloid cells single-cell RNA-seq analysis data from tdLN of TC-1 tumor-bearing mice immun

Single-cell RNA sequencing data from myeloid cells isolated from tumor-draining lymph nodes of TC-1 tumor-bearing mice. The dataset, 166.0 MB in size, was generated by Thanh Tran Quang and last updated in April 2026. Samples were processed using the 10x Genomics Chromium platform after mice received different peritumoral vaccination treatments.

Use Cases

• Analyzing myeloid cell population heterogeneity based on single-cell transcriptomes from lymph nodes.
• Comparing gene expression profiles between PBS, mR-E, and mR-DEF vaccination groups mentioned in the description.
• Investigating immune responses to TC-1 tumors based on the described experimental model.
• Benchmarking single-cell RNA-seq analysis pipelines using data from the 10x Genomics platform.

Strengths

• Data is shared under a permissive CC-BY-4.0 license.
• Experimental details are provided, including mouse strain (C57BL/6), vaccination doses, and use of the 10x Genomics platform.
• File size is 166.0 MB, indicating a medium-scale dataset.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect experimental bias inherent to the specific mouse model and vaccination protocol.

Provenance

Source

figshare

Collection Method

Single-cell isolation from lymph nodes followed by processing on the 10x Genomics Chromium platform.

Time Range

Experimental timeframe not specified; dataset last updated in 2026.

Freshness

Last updated 2026-04-30 08:05:58; freshness should be verified.

Geography

Laboratory study; geographic location not specified.