N-EtFOSA Exposure Effects on Zebrafish Microbiome and Behavior

Zebrafish larvae were exposed to PFOS, N-EtFOSA, or PFOSAmS at concentrations from 0.07–15 μM between 5 and 6 days post fertilization. Sebastian Gutsfeld published this dataset on figshare under a CC-BY-NC-4.0 license, last updated on 2026-05-13. The research investigates microbiome-dependent behavioral effects and metabolite changes resulting from perfluorooctane sulfonamide exposure.

Use Cases

• Modeling concentration-response relationships for chemical exposure based on described PFOS, N-EtFOSA, and PFOSAmS dose ranges
• Investigating microbiome-mediated behavioral modifications based on comparisons between axenic and conventionally colonized zebrafish cohorts
• Analyzing metabolite conversion pathways based on detected levels of FOSA and FOSAA in different colonization states

Strengths

• Dataset includes multiple chemical exposure conditions (PFOS, N-EtFOSA, PFOSAmS) across specified concentration ranges
• Experimental design compares axenic, conventionally colonized, and conventionalized larval states to isolate microbiome effects
• Chemical analysis results for metabolites like FOSA and FOSAA are included

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment for large-scale analyses

Provenance

Source

figshare

Collection Method

Experimental exposure of zebrafish larvae to perfluorooctane sulfonamides and subsequent behavioral and chemical analysis.

Freshness

Last updated 2026-05-13 23:03:56; freshness should be verified