Lysosomal Glycosidase Secretion Measurements from Single Living Macrophages

A dataset from figshare describes a novel methodology for quantifying lysosomal enzyme secretion from individual living cells. The data, authored by Yu-Ting Qi and last updated on 2026-05 14, likely contains measurements from experiments using hybrid nanowire-nanopipette sensors and artificial substrates. The 5.7 MB ZIP file holds results from monitoring glycosidase secretion induced by frustrated phagocytosis in macrophages.

Use Cases

• Modeling real-time lysosomal enzyme secretion dynamics based on the described quantitative assessment methodology.
• Analyzing cell-to-cell variability in glycosidase secretion based on single-cell measurements from living macrophages.
• Developing machine learning models for immune homeostasis prediction based on features of secretory lysosome activity.
• Benchmarking new sensor technologies for single-cell analysis based on the described nanowire-nanopipette platform.

Strengths

• Data is derived from an innovative methodology enabling real-time, quantitative monitoring of enzyme secretion from single living cells, as described.
• Dataset is focused on a specific biological process (lysosomal glycosidase secretion) with clear experimental induction (frustrated phagocytosis).
• File size is 5.7 MB, indicating a manageable download and storage footprint.

Limitations

• Row count is unknown, which may limit suitability assessment for statistical analysis.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

figshare, author Yu-Ting Qi.

Collection Method

Experimental data from a strategy combining artificial substrates and hybrid nanowire-nanopipette sensors.

Time Range

null

Freshness

Last updated 2026-05-14 08:46:33; freshness should be verified.

Geography

null