NeuralliTM-CORE: Mouse Model Data on Probiotic Effects in DSS-Induced Colitis

Experimental data from a study evaluating the multi-strain probiotic NeuralliTM-CORE in a dextran sulfate sodium (DSS)-induced colitis mouse model. The dataset includes measurements of disease activity, body weight, histopathology, cytokine levels, and microbiota analysis. It was authored by Fu-Sheng Deng and last updated on 2026-05 19.

Use Cases

• Analyze correlations between specific microbial taxa and colitis severity based on the described microbiota analysis.
• Model the attenuation of inflammatory markers like PTX2 and CHI3L1 based on cytokine profiling results.
• Investigate the recovery dynamics of microbial diversity (α-diversity) during the acute and recovery phases of colitis.
• Study the association between Muribaculaceae family members and inflammation reduction as suggested in the findings.

Strengths

• Dataset size is 815.6 MB, indicating a medium-scale collection of experimental results.
• License is CC-BY-4.0, permitting broad sharing and reuse with attribution.
• Description details specific measured outcomes: disease activity index, body weight loss, colonic histopathology, and cytokine levels.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is derived from a controlled mouse model, which may limit direct applicability to human studies.

Provenance

Source

figshare

Collection Method

Data generated from a preclinical mouse model study involving DSS-induced colitis and probiotic supplementation.

Time Range

null

Freshness

Last updated 2026-05-19 07:34:13; freshness should be verified.

Geography

null