NeuralliTM-CORE: Mouse Gut Microbiota and Cytokine Data from DSS-Induced Colitis Study

483.3 MB of data from a study evaluating the multi-strain probiotic NeuralliTM-CORE in a dextran sulfate sodium (DSS)-induced colitis mouse model. The dataset includes results on disease activity, body weight, histopathology, cytokine profiling, and 16S microbiota analysis. It was authored by Fu-Sheng Deng and last updated on 2026-05-19 under a CC-BY-4.0 license.

Use Cases

• Correlating specific microbial taxa like Duncaniella and Muribaculum with colitis severity scores.
• Analyzing the relationship between cytokine levels (PTX2, CHI3L1, CXCL13, MMP-2) and disease activity index.
• Modeling the impact of probiotic pre-supplementation on the recovery of microbial alpha-diversity after inflammatory insult.
• Investigating the attenuation of histopathological damage in the colon linked to probiotic treatment.

Strengths

• Dataset size of 483.3 MB suggests it contains detailed experimental results.
• Includes multiple data modalities: clinical scores, cytokine levels, and microbiota analysis.
• Explicitly describes a controlled mouse model with a two-week pre-supplementation period.

Limitations

• Row count and specific column definitions are unknown, requiring inspection after download.
• Data is from a specific animal model (DSS-induced colitis in mice), which may limit direct human translation.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

Fu-Sheng Deng via figshare

Collection Method

Experimental data from a controlled mouse study using DSS-induced colitis and probiotic intervention.

Freshness

Last updated 2026-05-19 08:03:36; freshness should be verified.