Mycoplasma Pneumoniae Biomarkers in Children with Pulmonary Consolidation

A retrospective case-control study of 81 children with acute-phase Mycoplasma pneumoniae pneumonia, categorized into consolidation (n=41) and non-consolidation (n=40) groups. The dataset includes bronchoalveolar lavage fluid measurements for oxidative stress biomarkers (MDA, SOD, GSH-Px, AOPP) and inflammatory markers. The data was authored by Junlin Zhao and last updated on 2026-04-13.

Use Cases

• Train models to predict pulmonary consolidation based on oxidative stress biomarker levels.
• Analyze biomarker network interactions using Gaussian graphical models as described.
• Investigate the mediating role of malondialdehyde between neutrophil-to-lymphocyte ratio and clinical outcomes.
• Explore associations between host inflammatory markers and extra-pulmonary organ involvement.

Strengths

• Includes specific biomarker measurements with median values and interquartile ranges reported for both patient groups.
• Dataset contains results from mediation analysis (indirect effect = 0.229, mediation proportion = 48.0%) and network modeling (density increased by 72.5%).
• Study design clearly defined with 81 enrolled children split into case and control groups.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Authors note findings are from a single-center retrospective study and require validation in larger prospective cohorts.

Provenance

Source

figshare, authored by Junlin Zhao.

Collection Method

Retrospective case-control study collecting bronchoalveolar lavage fluid samples.

Time Range

Study period not specified; data reflects acute-phase infection.

Freshness

Last updated 2026-04-13 06:24:31; freshness should be verified.

Geography

Geographic coverage of the single-center study is not specified.