Synthetic Polymer MALDI Methods Database from 1988 to 2011

NIST Synthetic Polymer MALDI Methods Database contains over 1250 documented polymer/matrix combinations for matrix-assisted laser desorption ionization mass spectrometry. The methods are compiled from peer-reviewed literature covering the period from 1988 through 2011. Each entry includes literature citations and Digital Object Identifiers (DOIs) where available.

Use Cases

• Analyze polymer/matrix combination trends over the 1988-2011 period to identify historical methodological shifts.
• Link methods to original literature using the provided Digital Object Identifier (DOI) and citation data for source verification.
• Categorize over 1250 entries by the five main polymer groups (A-E) based on elemental composition for material science studies.
• Cross-reference matrix compounds using provided Chemical Abstracts Service (CAS) numbers for chemical property lookup.

Strengths

• Contains over 1250 specific polymer/matrix combinations, providing a substantial reference corpus.
• Covers a long temporal range of 24 years, from 1988 to 2011, documenting methodological evolution.
• Entries are sourced from peer-reviewed scientific literature, enhancing reliability.
• Provides structured categorization into five main polymer groups based on chemical composition.

Limitations

• The database is not comprehensive, as acknowledged by NIST, and lacks methods for many IUPAC polymer classes.
• Coverage is significantly lower for areas like dendrimers, nanoparticles, polysaccharides, and homopolymer polypeptides.
• Data is static with the latest methods from 2011, potentially missing over a decade of recent advancements.

Provenance

Source

National Institute of Standards and Technology (NIST).

Collection Method

Methods extracted from peer-reviewed scientific literature.

Time Range

1988 to 2011.

Freshness

Last updated in July 2022, but methodological data coverage ends in 2011.