Nitrite Assimilation Enzyme NirD Regulates (p)ppGpp Homeostasis in Xanthomonas campestris

Harvard Dataverse hosts data from a study on the stringent response in the plant pathogen Xanthomonas campestris pv. campestris strain 8004. The research, authored by Shi, Jia, investigates the regulatory role of the nitrite reductase subunit NirD in modulating (p)ppGpp alarmone levels under nitrogen limitation. The dataset was last updated on April 14, 2026.

Use Cases

• Modeling the regulatory circuit between NtrC, relA, and NirD based on the described molecular interactions.
• Analyzing gene expression patterns for relA and nirD under nitrogen-limited conditions described in the study.
• Investigating protein-protein interaction networks involving the TGS and hydrolase domains of RelA and NirD.
• Studying the integration of nitrogen sensing with the stringent response in aerobic plant pathogens.

Strengths

• Data originates from a specific, peer-reviewed research study on Xanthomonas campestris pv. campestris strain 8004.
• The dataset description provides a detailed molecular mechanism linking nitrogen limitation to (p)ppGpp homeostasis.
• Last updated date is explicitly provided: 2026-04 14 20:35:57.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count and file size are unknown, which may limit suitability assessment.
• The dataset is focused on a single bacterial strain, limiting generalizability.

Provenance

Source

Harvard Dataverse, author Shi, Jia.

Collection Method

Likely contains experimental data from a study on bacterial genetics and metabolism.

Time Range

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Freshness

Last updated 2026-04-14 20:35:57.

Geography

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