Non-Human Primate Toxicity Study of P2 Polymer, 2023-2025

A preclinical toxicity study of the empty P2 poly(2-oxazoline) block copolymer in Rhesus Macaques. The dataset includes results from low-dose (30 mg/kg) and high-dose (90 mg/kg) trials conducted in July 2023 and January 2025, respectively, on four named subjects. The data was authored by Jacob Ramsey and last updated in April 2026.

Use Cases

• Assessing polymer biocompatibility based on the described dose-response trials
• Modeling toxicity thresholds based on the specified low (30 mg/kg) and high (90 mg/kg) doses
• Comparing preclinical safety outcomes across different non-human primate subjects
• Supporting regulatory submissions with documented in-vivo toxicity data

Strengths

• Study includes specific dose levels (30 mg/kg and 90 mg/kg) for comparison
• Data covers two distinct time points (July 2023 and January 2025)
• Subjects are identified by name (Kiki, Nina, Bertha, Gertrude), suggesting individual-level tracking

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

ODUM Harvested Dataverse

Collection Method

Preclinical in-vivo study in Rhesus Macaques

Time Range

2023-2025

Freshness

Last updated 2026-04-27 03:10:53; freshness should be verified

Geography

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