Barth Syndrome Preclinical Study Data on Omega-3 Supplementation and Muscle Mitochondria

A preclinical research dataset investigating the effects of omega-3 fatty acid supplementation on skeletal muscle mitochondrial function in a model of Barth syndrome. The dataset, authored by Trisha J. Grevengoed and last updated in April 2026, is hosted on figshare and comprises 16.5 GB of data files. It likely contains experimental results from in vitro studies and a muscle-specific knockout mouse model.

Use Cases

• Analyzing the relationship between omega-3 supplementation and mitochondrial respiration parameters based on the described functional model.
• Investigating compensatory changes in phospholipid species beyond cardiolipin based on the description of complex regulation.
• Modeling the impact of tafazzin gene knockout on lean mass and stress response based on the described mouse phenotype.

Strengths

• Dataset is 16.5 GB in size, indicating substantial data volume.
• Released under a permissive CC-BY-4.0 license for broad reuse.
• Last updated date of 2026-04-27 suggests recent maintenance.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely contains experimental data from in vitro assays and a TAZ muscle-specific knockout mouse model, as described.

Time Range

null

Freshness

Last updated 2026-04-27 14:55:30.

Geography

null