OpenTME: Spatial Tumor Microenvironment Profiles from TCGA

OpenTME is an open-access project by Aignostics providing spatial outputs for whole slide images from The Cancer Genome Atlas (TCGA). It is powered by the Atlas H&E-TME foundation model-based application for computational pathology. The dataset was last updated on 2026-04-15.

Use Cases

• Training machine learning models for spatial analysis of tumor tissue based on whole slide images.
• Correlating spatial tumor microenvironment features with genomic data from TCGA.
• Developing computational pathology applications for cancer research based on foundation model outputs.

Strengths

• Data originates from the authoritative The Cancer Genome Atlas (TCGA) program.
• Spatial outputs are generated by the Atlas H&E-TME foundation model-based application.

Limitations

• Row count, column definitions, and file formats are unknown, limiting suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

The Cancer Genome Atlas (TCGA)

Collection Method

Spatial outputs generated by the Atlas H&E-TME application from formalin-fixed, paraffin-embedded whole slide images.

Freshness

Last updated 2026-04-15 18:00:55; freshness should be verified.