Oral Microbiome Dysbiosis of Porphyromonas gingivalis in Oral Diseases

96 oral swab samples collected from six groups: healthy nonsmokers, healthy smokers, periodontitis, oral leukoplakia, oral squamous cell carcinoma, and radiation-induced oral mucositis. Quantitative real-time PCR was performed to assess the relative abundance of the fimA I genotype. The dataset was created by Ajay Kumar Verma and last updated on May 22, 2026.

Use Cases

• Assessing fimA I genotype abundance as a biomarker for oral squamous cell carcinoma based on qPCR results.
• Comparing microbial dysbiosis across oral disease conditions like periodontitis and radiation-induced oral mucositis.
• Investigating the role of Porphyromonas gingivalis in oral leukoplakia progression.
• Evaluating potential therapeutic targets for oral diseases based on fimA I expression levels.

Strengths

• Includes 96 oral swab samples from six distinct clinical groups.
• Quantitative real-time PCR results provide a specific measure of fimA I genotype abundance.
• Statistical significance (p < 0.05) reported for comparisons in RIOM and OSCC.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic or clinical bias inherent to the specific study cohort.

Provenance

Source

Ajay Kumar Verma

Collection Method

Oral swab samples collected and analyzed via quantitative real-time PCR.

Freshness

Last updated 2026-05-22 02:52:50; freshness should be verified.