Organocatalytic Synthesis Data for Oxindole-Based Bridged Biaryls

A 564.6 KB dataset contains CIF files documenting the organocatalytic asymmetric synthesis of oxindole-based bridged biaryls. Author Namrata Kotwal published this research data on figshare in 2026, detailing a method for constructing molecules with three contiguous stereocenters and a chiral axis.

Use Cases

• Analyze CIF structural data to validate the three contiguous stereocenters and chiral axis in synthesized oxindole-fused biaryl-bridged scaffolds.
• Use reaction data to correlate substrate scope with high yields and enantioselectivities reported for the organocatalyzed protocol.
• Examine CIF files to study the structural relevance of bridged biaryls exhibiting both central and axial chirality simultaneously.

Strengths

• Data is recent, last updated in March 2026.
• Focuses on a novel, previously unreported method for enantioselective construction of oxindole-based bridged biaryls.
• Documents synthesis under mild reaction conditions for a broad range of substrates.

Limitations

• The dataset is small at 564.6 KB, indicating limited scope and likely a small number of molecular structures.
• Contains only CIF format files, requiring specialized chemistry software for analysis.
• No tabular data or column descriptions are provided, limiting quantitative analysis.

Provenance

Source

figshare

Collection Method

Experimental research data from an organocatalyzed enantio- and diastereoselective synthesis protocol.

Time Range

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Freshness

2026-03-14

Geography

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