SARS-CoV-2 N Protein Interaction Data for ZBP1-Mediated Necroptosis

Original research data investigates the mechanism of SARS-CoV-2-induced lung injury. The dataset, authored by GONG xiaohua and last updated in June 2026, includes findings on the viral nucleocapsid protein activating ZBP1/RIPK3-dependent necroptosis. It is shared under a CC-BY-4.0 license and comprises 3.8 MB of data in PDF and PZFX formats.

Use Cases

• Validate bioinformatics predictions of protein-protein interactions based on the described RHIM-like motif.
• Model inflammatory signaling pathways based on the described ZBP1/RIPK3/MLKL activation cascade.
• Identify potential drug targets based on the described N-ZBP1 interaction axis.
• Correlate in vitro and in vivo necroptosis activation data based on the described experimental findings.

Strengths

• Data is associated with a specific, peer-reviewed research finding on SARS-CoV-2 pathogenesis.
• Files are provided in two formats (PDF, PZFX), potentially offering both narrative and structured data.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 3.8 MB size suggests a small dataset, potentially limiting statistical power for some analyses.

Provenance

Source

figshare

Collection Method

Likely contains experimental and bioinformatics analysis data from the described research.

Freshness

Last updated 2026-06-01 08:44:08; freshness should be verified.