Mouse Hippocampus Differentially Expressed Genes After Status Epilepticus

Aggregating a list of differentially expressed genes (DEGs) identified in the hippocampus of mice 24 hours after status epilepticus. The data is provided in an XLSX file of 124.1 KB, authored by Hui-Ling Tang and shared under a CC BY 4.0 license. The specific row count and column structure are not detailed in the provided input.

Use Cases

• Identify candidate genes from the DEG list for further validation in epilepsy research models.
• Perform pathway enrichment analysis using the list of differentially expressed genes to understand biological processes affected by status epilepticus.
• Compare this DEG list with other temporal points (e.g., SE 48h) to study the progression of gene expression changes in the mouse hippocampus.

Strengths

• Data is focused on a specific biological context: gene expression in the mouse hippocampus 24 hours after status epilepticus.
• The dataset is shared under a permissive CC BY 4.0 license, facilitating reuse and distribution.
• File size of 124.1 KB indicates a manageable, focused dataset for targeted analysis.

Limitations

• The dataset is very small at 124.1 KB, indicating a limited scope and likely a small list of genes rather than a full expression matrix.
• Lack of column descriptions or sample data prevents understanding of the available metrics (e.g., log fold change, p-value) for each gene.
• The input provides no information on sample size, replication, or the statistical methods used to define the DEGs, limiting reproducibility assessment.

Provenance

Source

Figshare, authored by Hui-Ling Tang.

Collection Method

Presumably derived from a gene expression analysis (e.g., RNA-seq or microarray) comparing mouse hippocampus samples after status epilepticus to controls.

Time Range

Samples collected 24 hours after status epilepticus induction.

Freshness

Last updated on 2026-03-20.