ADME and CYP Inhibition Profiles for Bioactive Compounds

PreADME and SwissADME tools generated absorption, distribution, elimination, and toxicity profiles for bioactive compounds. The dataset includes predicted inhibition of CYP2C19 and CYP2C9 enzymes. Courage Siame authored this 5.5 KB Excel file, last updated in May 2026.

Use Cases

• Predicting drug bioavailability based on ADME profiles
• Assessing potential drug-drug interactions based on CYP2C19 and CYP2C9 inhibition
• Ranking compound safety for drug discovery based on toxicity profiles
• Modeling compound distribution and elimination kinetics

Strengths

• Profiles generated using established computational tools PreADME and SwissADME
• Data is openly licensed under CC-BY-4.0
• File size is 5.5 KB, indicating a focused and manageable dataset

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Description metadata is limited; actual data quality requires manual inspection after download

Provenance

Source

figshare

Collection Method

Profiles assessed using PreADME; CYP2C19 and CYP2C9 inhibition predicted by SwissADME.

Freshness

Last updated 2026-05-06 17:26:48; freshness should be verified