Adverse Drug Reactions During MAC-PD Treatment, 2010-2023 Patient Cohort

420 patients treated for Mycobacterium avium complex pulmonary disease (MAC-PD) between 2010 and 2023 were analyzed in a retrospective cohort study by Hye Young Hong. The dataset likely contains patient records used to identify risk factors for early treatment interruption (ETI) and its impact on mortality. ETI occurred in 30% of patients and was associated with adverse drug reactions and nutritional status.

Use Cases

• Modeling risk factors for early treatment interruption based on adverse drug reactions and nutritional index.
• Analyzing the association between treatment duration and mortality in MAC-PD patients.
• Investigating the prevalence and impact of grade 2 or higher adverse drug reactions in long-term antibiotic therapy.

Strengths

• Dataset is based on a cohort of 420 patients, providing a substantive sample size for analysis.
• Covers a 13-year time range (2010-2023), allowing for longitudinal outcome assessment.
• Analysis includes specific, quantified risk factors (e.g., aOR: 5.65 for ADRs).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect temporal or institutional bias inherent to a single retrospective study.

Provenance

Source

Hye Young Hong via figshare.

Collection Method

Retrospective cohort study of hospital records.

Time Range

2010 to 2023

Freshness

Last updated 2026-05-27 17:32:07; freshness should be verified.