Agonistic Transcription Activity for Full-Length and Truncated ERα in a Luciferase Assay

5.5 KB of data in XLS format, uploaded by Xiaohui Liu on figshare in June 2026. The dataset contains results from a luciferase reporter gene assay measuring the agonistic transcription activation activity of full-length ERα and a truncated variant, desNTD(AF-1)-ERα. The specific number of rows and columns is not provided in the metadata.

Use Cases

• Compare the transcriptional activity of full-length ERα versus a truncated variant based on the luciferase assay results.
• Model dose-response relationships for ERα agonists based on the reporter gene assay data.
• Validate computational predictions of protein domain function using experimental activity measurements for the AF-1 domain.

Strengths

• Data is openly available under a CC-BY-4.0 license.
• The dataset is small (5.5 KB), facilitating quick download and inspection.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Xiaohui Liu via figshare.

Collection Method

Likely generated from a luciferase reporter gene assay in a laboratory setting.

Freshness

Last updated 2026-06-01 17:41:29; freshness should be verified.