MSMI Data from GBD 2021: Global Maternal Sepsis Burden 1990-2021

From 1990 to 2021, this dataset contains original data on maternal sepsis and other maternal infections (MSMI) from the Global Burden of Disease 2021 study. It was uploaded by Anqi Jiang and includes results from temporal trend analysis and Mendelian randomization. The data is packaged in a 37.4 MB ZIP file.

Use Cases

• Analyzing global and regional temporal trends in maternal sepsis burden based on the 1990-2021 time series.
• Forecasting future disease patterns using ARIMA and BAPC model outputs mentioned in the description.
• Investigating causal relationships between inflammatory biomarkers and MSMI risk based on the multivariable Mendelian randomization results.
• Comparing disease burden across Socio-demographic Index (SDI) regions based on the analysis of low-SDI regions.

Strengths

• Data spans a 32-year time range from 1990 to 2021.
• Integrates population-level trend analysis with causal inference via Mendelian randomization.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and specific column definitions are unknown, requiring inspection after download.
• The 37.4 MB file size suggests a relatively small dataset, which may limit the scope of analysis.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Global Burden of Disease (GBD) 2021 study.

Collection Method

Original data from GBD, analyzed with ARIMA, Bayesian age–period–cohort (BAPC), and two-sample multivariable Mendelian randomization models.

Time Range

1990 to 2021

Freshness

Last updated 2026-05-27 17:51:06; freshness should be verified.

Geography

Global, with analysis by region and Socio-demographic Index (SDI).