Experimental Mouse Data for Difelikefalin in Acute Kidney Injury Models

Yoshiharu Sawanobori published raw data on figshare in April 2026. The dataset contains the underlying data used to create figures for a study on the renal protective effects of difelikefalin in murine models of critical illness. It includes results from lipopolysaccharide-induced, cecum ligation and puncture-induced, and renal ischemia/reperfusion models.

Use Cases

• Replicate statistical analyses from the associated publication based on the raw figure data.
• Conduct secondary analysis on drug efficacy in sepsis models based on the described experimental outcomes.
• Validate the reported effects on urine flow and mortality rates based on the underlying measurements.
• Explore correlations between neural crest-derived cell markers and cytokine expression based on the described cellular assays.

Strengths

• Data is directly linked to a published experimental study on a specific pharmacological agent.
• File is openly available under a CC-BY-4.0 license for reuse and redistribution.
• Dataset is small (26.3 KB), facilitating quick download and inspection.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset's scope is limited to the specific experiments described in the accompanying study.

Provenance

Source

figshare, author Yoshiharu Sawanobori

Collection Method

Experimental data collected from mouse models of acute kidney injury.

Time Range

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Freshness

Last updated 2026-04-21 17:45:19; freshness should be verified.

Geography

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