AlphaFold3: Predicted Transcription Complex with Pol II and DNA Fragment

Jie Hao published a predicted transcription complex structure on figshare in April 2026. The dataset is a 823.2 KB ZIP file containing AlphaFold3 predictions for a complex of RNA Polymerase II and a DNA fragment. The specific number of structures or rows is not provided.

Use Cases

• Validate AlphaFold3 predictions for large protein-nucleic acid complexes based on the described Pol II-DNA structure.
• Study the structural interface between RNA Polymerase II and DNA based on the predicted transcription complex.
• Use as a reference model for molecular dynamics simulations of transcription initiation based on the predicted atomic coordinates.
• Benchmark other protein structure prediction tools against this AlphaFold3 output for transcription-related complexes.

Strengths

• Dataset is licensed under CC-BY-4.0, permitting broad reuse with attribution.
• File size is 823.2 KB, indicating a relatively small and quick download.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Predicted using AlphaFold3, an AI system for biomolecular structure prediction.

Freshness

Last updated 2026-04-30 17:51:58; freshness should be verified.