AlphaMissense-Based Pathogenicity Assessment of Selected nsSNPs. The dataset was authored by Arwa Ibrahim Alwabran and is available on figshare under a CC-BY-4.0 license. It was last updated on 2026-05-21.
Use Cases
- Predicting disease-causing potential of genetic variants based on AlphaMissense scores
- Benchmarking pathogenicity prediction tools against AlphaMissense assessments
- Prioritizing non-synonymous SNPs for further clinical investigation
Strengths
- The dataset is openly licensed (CC-BY-4.0), facilitating reuse.
- It leverages the AlphaMissense model, a state-of-the-art tool for pathogenicity prediction.
Limitations
- The dataset is very small (5.5 KB), indicating a limited scope.
- Row count and column-level documentation are unknown, which may limit suitability assessment.
- Description metadata is limited; actual data quality requires manual inspection after download.