VEEV Mouse Model: Longitudinal Neuropathological and Behavioral Scores

C57BL/6 mice were intranasally infected with Venezuelan equine encephalitis virus (VEEV) TC-83. The dataset, created by Morgen VanderGiessen and last updated in April 2026, likely contains longitudinal neuropathological, behavioral, and single-cell transcriptomic measurements collected up to 106 days post-infection.

Use Cases

• Modeling chronic motor dysfunction based on longitudinal behavioral scores mentioned in the description
• Analyzing correlations between acute neurological symptoms and persistent memory impairment
• Investigating glia cell activation and neuron loss in the hippocampus post-infection
• Studying alterations in synaptogenic signaling gene expression from single-cell transcriptomic data

Strengths

• Data is longitudinal, tracking changes up to 106 days post-infection
• Integrates multiple data modalities: neuropathological, behavioral, and transcriptomic
• License is CC-BY-4.0, permitting broad reuse

Limitations

• Dataset is very small at 5.5 KB, indicating limited scope
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare, author Morgen VanderGiessen

Collection Method

Experimental data from C57BL/6 mice intranasally infected with VEEV TC-83 virus

Time Range

Observations up to 106 days post-infection

Freshness

Last updated 2026-04-08 17:53:49

Geography

Laboratory study; geographic scope is not specified