Antagonistic Transcriptional Activity of ERα Variants in a Luciferase Assay

5.5 KB of data in XLS format, uploaded by Xiaohui Liu, details the antagonistic transcriptional inhibitory activity of full-length ERα and a desNTD(AF-1)-ERα variant. The dataset was last updated on June 1, 2026, and is shared under a CC-BY-4.0 license.

Use Cases

• Compare the inhibitory potency of full-length ERα versus a truncated variant based on the luciferase reporter assay data.
• Model dose-response relationships for transcriptional antagonism based on the assay results.
• Validate computational predictions of protein domain function using the experimental activity data.

Strengths

• Dataset is small (5.5 KB), facilitating quick download and inspection.
• Data is shared under a permissive CC-BY-4.0 license, allowing for broad reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Xiaohui Liu

Collection Method

Data likely originates from a luciferase reporter gene assay.

Freshness

Last updated 2026-06-01 17:41:30; freshness should be verified.