Genetic SNP Association Analysis for Leprosy Clinical Forms in Two Brazilian Cities

Association analysis by multinomial logistic regression models for associated SNPs in CACNA2D3, IRGM and LRRK2 with leprosy clinical forms in Manaus (MAN) and Rondonópolis (ROO). The dataset, authored by Isabela Espasandin, is a 17.5 KB XLS file last updated on 2026-04-27 and shared under a CC-BY-4.0 license.

Use Cases

• Training genetic risk prediction models based on SNP associations with clinical forms.
• Replicating association studies for leprosy susceptibility genes in specific populations.
• Conducting meta-analyses on genetic factors for leprosy using the reported association statistics.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• Focuses on three specific genes (CACNA2D3, IRGM, LRRK2) associated with leprosy.
• Analysis is geographically anchored to two Brazilian cities (Manaus and Rondonópolis).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 17.5 KB size indicates a very limited scope of data.

Provenance

Source

figshare

Collection Method

Association analysis by multinomial logistic regression models.

Time Range

null

Freshness

Last updated 2026-04-27 17:45:59; freshness should be verified.

Geography

Manaus (MAN) and Rondonópolis (ROO), Brazil.