Association Analysis of SNPs with Leprosy Clinical Forms in Rio de Janeiro

A 17.5 KB Excel file containing results from multinomial logistic regression models analyzing the association of SNPs in the CACNA2D3, IRGM, and LRRK2 genes with different clinical forms of leprosy. The dataset was authored by Isabela Espasandin and last updated on 2026-04 27. It is shared under a CC-BY-4.0 license on the figshare platform.

Use Cases

• Validate genetic associations for leprosy clinical forms based on the described SNP analysis.
• Compare the role of CACNA2D3, IRGM, and LRRK2 genes in disease manifestation based on the regression results.
• Perform meta-analysis by integrating these Rio de Janeiro-specific findings with other genetic studies.
• Investigate potential biomarkers for leprosy clinical classification based on the identified SNPs.

Strengths

• Dataset is openly licensed under CC-BY-4.0, permitting reuse and redistribution.
• Focus on a specific geographic cohort (Rio de Janeiro) provides localized genetic insights.
• Analysis targets three specific genes (CACNA2D3, IRGM, LRRK2) with known immunological relevance.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 17.5 KB file size suggests a very limited scope, likely containing summary statistics rather than raw genotype data.

Provenance

Source

figshare

Collection Method

Association analysis by multinomial logistic regression models.

Time Range

null

Freshness

Last updated 2026-04-27 17:45:58; freshness should be verified.

Geography

Rio de Janeiro, Brazil