Genetic Variant Association with Paracoccidioidomycosis from Meta-Analysis

Sanderson da Silva Coelho published a dataset on figshare in March 2026. It presents results from a meta-analysis of studies on the association of single nucleotide variants (SNVs) with paracoccidioidomycosis (PCM). The table includes genetic models, genotype frequencies, odds ratios with confidence intervals, p-values, and information criteria.

Use Cases

• Assessing genetic risk factors for paracoccidioidomycosis based on odds ratios and confidence intervals.
• Comparing statistical models for genetic association based on the AIC and BIC information criteria.
• Evaluating genotype frequencies in patients versus controls for specific cytokine genes like IFNG, IL4, and TNF.
• Testing for deviations from Hardy-Weinberg equilibrium in genetic association studies.

Strengths

• Includes multiple statistical measures: odds ratios, 95% confidence intervals, p-values, and FDR correction.
• Compares five genetic models (codominant, dominant, recessive, overdominant, log-additive) for each variant.
• File is openly available under a CC-BY-4.0 license.

Limitations

• Row count and specific column names are unknown, limiting suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Dataset is very small at 12.9 KB, indicating limited scope.

Provenance

Source

figshare, author Sanderson da Silva Coelho.

Collection Method

Data derived from a systematic review and meta-analysis of existing studies.

Time Range

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Freshness

Last updated 2026-03-19 17:27:20; freshness should be verified.

Geography

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