<p>Background characteristics of patients with OD.</p>

A 2026 study by Nobuyoshi Sugiyama compares adenylate cyclase activity and basic clinical data between 30 Japanese pediatric patients with orthostatic dysregulation and 20 healthy adult controls. The dataset likely contains measurements such as blood pressure, pulse rate, and adenylate cyclase activity levels under different stimulants. It is published under a CC-BY-4.0 license on figshare.

Use Cases

• Investigating biochemical markers for orthostatic dysregulation based on adenylate cyclase activity levels.
• Comparing clinical profiles between POTS and delayed orthostatic hypotension patients based on systolic blood pressure and pulse rate.
• Developing diagnostic strategies for orthostatic dysregulation based on the correlation between adenylate cyclase activity and patient subtypes.

Strengths

• Includes data from 30 patients with specific subtype breakdown (21 POTS, 8 delayed orthostatic hypotension).
• Compares patient data against a control group of 20 healthy adults.
• Measures adenylate cyclase activity under multiple stimulants (isoproterenol, adrenaline) at different concentration points.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The sample size of 30 patients is relatively small, and the control group consists of adults, not pediatric peers.

Provenance

Source

Nobuyoshi Sugiyama via figshare

Collection Method

Clinical study analyzing blood samples and vital signs from diagnosed patients and reported healthy controls.

Freshness

Last updated 2026-04-30 17:39:14; freshness should be verified.

Geography

Japan (implied by focus on Japanese children)