Baloxavir Pharmacokinetics in Okinawa Rails

Mariko Miki's dataset contains plasma concentration and pharmacokinetic parameters for the prodrug Baloxavir marboxil in Okinawa rails (Hypotaenidia okinawae). It documents a single subcutaneous administration study, with data provided in an XLS file under a CC BY 4.0 license. The dataset was last updated in March 2026.

Use Cases

• Model plasma concentration time-course curves for Baloxavir marboxil in avian species.
• Estimate pharmacokinetic parameters like clearance or volume of distribution from the single-dose study.
• Compare drug metabolism metrics between avian and mammalian species using the provided concentration data.

Strengths

• Data is openly licensed under CC BY 4.0, facilitating reuse and sharing.
• The dataset provides specific pharmacokinetic data for the endangered Okinawa rail, a rare avian subject.
• It was updated recently, with a last modified date in March 2026.

Limitations

• The dataset is very small at 9.5 KB, indicating limited scope and likely a low number of observations.
• The sample size and number of animals used in the single-administration study are unknown.
• Data is confined to a single species and drug, limiting generalizability to other contexts.

Provenance

Source

Mariko Miki via figshare.

Collection Method

Data from a single subcutaneous administration pharmacokinetic study.

Freshness

Last updated 2026-03-23.

Geography

Study likely conducted in Japan, referencing the Okinawa rail.