Baseline Characteristics of Participants in Two African HIV Cohorts

A dataset of baseline characteristics for 67 participants from two African HIV cohorts (HVTN 503 and PP/COS). It contains pre-infection Th17 cell frequency measurements and subsequent disease progression markers, including CD4/CD8 ratios and viral load set points. The data was authored by Tosin E. Omole and last updated in April 2026.

Use Cases

• Analyze associations between pre-HIV Th17 cell levels and CD4 decline based on flow cytometry data.
• Compare HIV disease progression markers between South African and East African cohorts.
• Investigate sex-stratified differences in immune response to HIV infection.
• Model the relationship between pre-infection immune status and viral load set point.

Strengths

• Data is derived from two distinct cohorts totaling 67 participants.
• Includes quantified Th17 cell frequencies measured by flow cytometry.
• Contains longitudinal disease progression markers like CD4/CD8 ratios and hazard ratios.
• Released under a permissive CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 9.5 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Analysis of archived cryopreserved PBMCs from cohort participants.

Time Range

Samples collected within one year prior to HIV acquisition.

Freshness

Last updated 2026-04-24 18:20:33; freshness should be verified.

Geography

Participants from a South African cohort (HVTN 503) and an East African cohort (Partners Pre-exposure Prophylaxis/Couples’ Observational Study).