Baseline Results: Cost-Effectiveness Model for Advanced Liver Cancer Treatments

A 5.5 KB Excel file contains the model results for a cost-effectiveness analysis comparing two first-line treatments for advanced hepatocellular carcinoma. The analysis, authored by XueYin Xu and uploaded to figshare, uses a three-state partitioned survival model over a 10-year horizon with a 4.5% discount rate. It was last updated on May 14, 2026, and concludes that a dual-agent therapy is not cost-effective from the perspective of the Chinese healthcare system.

Use Cases

• Compare incremental cost-effectiveness ratios (ICERs) for oncology drug regimens based on the model's primary outcomes.
• Conduct sensitivity analyses on cost-effectiveness models using the parameters identified as influential, such as utility values and drug costs.
• Evaluate the economic viability of new cancer therapies against established treatments using partitioned survival model outputs.
• Assess the impact of willingness-to-pay thresholds on treatment adoption decisions in a specific healthcare system.

Strengths

• The model is based on results from a Phase III clinical trial, providing a foundation in empirical clinical data.
• A comprehensive sensitivity analysis was performed, including one-way and probabilistic methods, to test result robustness.
• The analysis uses a specific willingness-to-pay threshold (299,400 CNY) based on China's projected 2025 per capita GDP.

Limitations

• The dataset is very small (5.5 KB), suggesting it contains only summary model outputs, not patient-level or detailed trial data.
• Column-level documentation is absent; field semantics must be inferred after download from the model description.
• The data's scope is limited to a single economic model for one cancer type and two specific treatment regimens.

Provenance

Source

figshare

Collection Method

Constructed from a Phase III clinical trial using a three-state partitioned survival model.

Time Range

Model horizon of 10 years.

Freshness

Last updated 2026-05-14 17:39:57; freshness should be verified.

Geography

Perspective of the Chinese healthcare system.