CALDERA Predictions: Biological Validation for 93 UK Biobank Traits

Biological validation results for the top 20 gene predictions from the CALDERA tool across 93 traits in the UK Biobank. The 13.5 KB Excel file includes a 'QTL' column indicating the strongest quantitative trait locus evidence for each gene, as referenced in the Weeks et al. study. Author Marijn Schipper published this dataset on figshare in March 2026.

Use Cases

• Benchmarking gene prioritization tools based on biological validation results for 93 traits.
• Identifying likely causal genes based on the presence of the strongest QTL evidence in a locus.
• Validating CALDERA predictions against independent evidence from the UK Biobank.

Strengths

• Focuses on a specific validation task for the top 20 predictions from the CALDERA tool.
• Includes a 'QTL' column explicitly denoting the strongest evidence for each gene.
• Covers a substantial scope of 93 traits from the UK Biobank resource.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 13.5 KB size indicates a very limited, likely summary-level dataset.

Provenance

Source

figshare, author Marijn Schipper.

Collection Method

Biological validation results derived from UK Biobank data and the CALDERA gene prioritization tool.

Time Range

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Freshness

Last updated 2026-03-17 17:32:44; freshness should be verified.

Geography

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