NHANES CVD and Skin Cancer Mediation Analysis Data

7424 participants from the 2015-2018 NHANES survey provide data for investigating cardiovascular disease as a risk factor for non-melanoma skin cancer. The dataset includes measurements for inflammatory markers SIRI and SII, and obesity indices BMI and WWI, used in logistic regression and mediation analysis. Bootstrap tests confirm the stability of the mediation results linking CVD to NMSC through obesity and inflammation.

Use Cases

• Perform logistic regression to test CVD as a risk factor for NMSC using the 7424 NHANES participant records.
• Analyze the mediating role of inflammatory markers SIRI and SII on the association between CVD and NMSC.
• Investigate how obesity indices BMI and WWI partially mediate the relationship between CVD and NMSC.
• Replicate the bootstrap test for mediation analysis to confirm the stability of the obesity and inflammation pathways.

Strengths

• Data from 7424 participants provides a substantial sample for analysis.
• Includes specific biomarkers (SIRI, SII, BMI, WWI) for testing mediation hypotheses.
• Results are supported by bootstrap tests, confirming analytical stability.

Limitations

• Small file size (5.5 KB) suggests limited raw data or aggregated results only.
• Self-reported diagnoses of CVD and NMSC may introduce recall bias.
• Cross-sectional NHANES data from 2015-2018 limits causal inference.

Provenance

Source

National Health and Nutrition Examination Survey (NHANES)

Collection Method

Questionnaire combined with self-reported diagnoses from 7424 participants.

Time Range

2015 to 2018

Freshness

Data covers the period 2015-2018, with metadata last updated in 2026.

Geography

United States (NHANES)