Adverse Event Clinical Profiles for Aliskiren from VigiAccess

Clinical characteristics of adverse events for the hypertension drug aliskiren are detailed in this 9.5 KB Excel file. The dataset was created by Meirong Shan and last updated in April 2026, drawing from the WHO's VigiAccess database of global safety reports.

Use Cases

• Identify significant disproportionality signals for specific adverse event terms associated with aliskiren.
• Analyze the distribution of 607 preferred terms for adverse reactions reported for this drug.
• Examine clinical characteristics like patient demographics or outcomes (SOCs) among the reported cases.
• Conduct a retrospective quantitative analysis of aliskiren's safety profile using marketing surveillance data.

Strengths

• Data sourced from VigiAccess, a WHO database covering reports from over one billion people.
• Focus on a single drug (aliskiren) allows for a detailed, specific safety analysis.
• Structured in Excel format for straightforward tabular analysis.

Limitations

• The dataset is very small at 9.5 KB, indicating limited scope or aggregated summary data.
• Unknown row count prevents assessment of statistical power for rare event detection.
• Relies on spontaneous reporting data, which is subject to under-reporting and reporting bias.

Provenance

Source

WHO VigiAccess database.

Collection Method

Retrospective analysis of spontaneous adverse event reports.

Freshness

Last updated April 2026.

Geography

Global (implied by VigiAccess source).