Clinical Characteristics of Leprosy Patients with Trophic Ulcers in Jakarta

A 2026 case-control study of 82 adult leprosy patients (41 with trophic ulcers, 41 without) treated at a tertiary referral hospital in Jakarta, Indonesia. The dataset, published by Paulus Anthony Halim on figshare, compares serum vitamin D levels and VDR FokI polymorphism between patient groups and assesses their association with ulcer presence and severity.

Use Cases

• Analyze the association between serum vitamin D levels and trophic ulcer presence based on the measured 25(OH)D values.
• Investigate the relationship between VDR FokI genetic polymorphism and ulcer risk based on the PCR-RFLP genotype data.
• Examine the correlation between vitamin D status and ulcer severity based on the Pressure Ulcer Scale for Healing (PUSH) scores.
• Build predictive models for trophic ulcer risk in leprosy patients based on the combined clinical and genetic variables.

Strengths

• Includes specific, measured clinical variables: serum 25(OH)D levels and VDR FokI polymorphism genotypes.
• Contains a clearly defined case-control structure with 41 patients in each group.
• Data is associated with published statistical results, including odds ratios and p-values, providing context.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 9.5 KB, indicating a limited scope of 82 subjects.

Provenance

Source

Paulus Anthony Halim via figshare.

Collection Method

Data collected via a case-control study at a tertiary referral hospital in Jakarta, Indonesia. Serum levels measured by chemiluminescence assay, genetic analysis by PCR-RFLP.

Time Range

Study period not specified; dataset published in 2026.

Freshness

Last updated 2026-04-10 17:44:16; freshness should be verified.

Geography

Jakarta, Indonesia.