Clinical Outcomes and Economic Model for PFO Closure in Stroke Prevention

A model-based dataset comparing clinical outcomes and costs for percutaneous patent foramen ovale (PFO) closure versus medical management in cryptogenic stroke patients over a 30-year horizon. The dataset was authored by Chen Chen and last updated on March 17, 2026. It is a small Excel file (5.5 KB) licensed under CC-BY-4.0.

Use Cases

• Compare quality-adjusted life years (QALYs) gained between PFO closure and medical management based on the described model horizon.
• Analyze the incremental cost-effectiveness ratio (ICER) for stroke prevention strategies based on the described economic comparison.
• Model Markov cohort transitions between health states like minor and severe recurrent stroke based on the described framework.
• Evaluate the economic dominance of PFO closure programs based on the described cost-reduction claims.

Strengths

• Model horizon is explicitly defined as 30 years.
• License is clearly stated as CC-BY-4.0, permitting reuse.
• File size is small (5.5 KB), facilitating quick download and inspection.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, authored by Chen Chen.

Collection Method

Likely contains results from a modeled health economic analysis.

Time Range

Model horizon is 30 years.

Freshness

Last updated 2026-03 17:23:34; freshness should be verified.

Geography

Platform tags suggest a potential focus on China, but this is not explicitly confirmed in the core description.