Clinicopathological Characteristics of 26 Suspected Lynch Syndrome Patients

26 patient records detailing clinicopathological characteristics of individuals suspected of having Lynch syndrome who carry pathogenic variants, likely pathogenic variants, or promising variants of uncertain significance in DNA mismatch repair genes. The dataset was authored by Worrawit Wanitsuwan and last updated on May 11, 2026. It is shared under a CC-BY-4.0 license as a 13.5 KB Excel file.

Use Cases

• Correlate specific genetic variants with clinical presentation based on patient characteristics.
• Analyze the spectrum of pathological findings in suspected Lynch syndrome cases.
• Assess the clinical significance of variants of uncertain significance in MMR genes.
• Support genotype-phenotype studies for hereditary cancer syndromes.

Strengths

• Focuses on a specific, clinically relevant cohort of 26 suspected Lynch syndrome patients.
• Includes data on multiple variant types (PVs, LPVs, promising VUSs) in DNA MMR genes.
• Clinicopathological characteristics provide a link between genetic findings and disease presentation.

Limitations

• The dataset is very small (26 patients), limiting statistical power and generalizability.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Freshness

Last updated 2026-05-11 17:23:37; freshness should be verified.