Dupuytren Disease Collagen Biomarker Profile from Multi-Omic Pilot Study

68 serum proteins showed statistically significant differences between Dupuytren Disease patients and a healthy control group. This 9.5 KB dataset contains proteomic biomarker profiles and collagen epitope markers from a pilot study comparing plasma samples. The data was authored by Blake Hummer and last updated on March 18, 2026.

Use Cases

• Developing diagnostic biomarker panels based on the 68 significantly different serum proteins.
• Training classification models to distinguish Dupuytren Disease from controls using the described Diagnostic Proteomic Risk Scores (DPRS).
• Investigating collagen metabolism impairment by analyzing markers of Collagen I synthesis and degradation.
• Staging disease progression based on the hypothesis-based DPRS linked to age at first corrective procedure.

Strengths

• Includes results from analysis of 6995 serum protein aptamers.
• Generated two Diagnostic Proteomic Risk Scores (DPRS) with reported accuracies of 76.5% and 70.6%.
• Licensed under CC-BY-4.0 for open reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Dataset is very small at 9.5 KB, indicating limited scope.

Provenance

Source

figshare, author Blake Hummer.

Collection Method

Multi-omic study comparing Dupuytren Disease plasma with a healthy control group.

Time Range

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Freshness

Last updated 2026-03-18 17:26:15; freshness should be verified.

Geography

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