Complete Genomes Sequenced in This Study: 219 Neisseria Gonorrhoeae Isolates

A dataset of 219 complete genomes from phylogenetically diverse clinical isolates of Neisseria gonorrhoeae, assembled using long-read sequencing. It was created by QinQin Yu and last updated on 2026-05-11. The data was generated to overcome limitations of short-read sequencing for resolving the multiple copies of the opacity-associated (opa) gene family.

Use Cases

• Analyzing opa allele diversity and copy number based on the complete genome assemblies.
• Studying the correlation between genomic distance and opa allele sequence similarity across isolates.
• Investigating the reading frame status of opa genes to infer expression patterns.
• Comparing the evolutionary rate of a specific, rapidly evolving opa locus against other loci.
• Assessing the role of interspecies recombination in Neisseria gonorrhoeae opa diversity.

Strengths

• Contains 219 complete genomes, providing a substantial sample size for analysis.
• Uses long-read sequencing, which resolves multiple copies of the opa gene family that short-read methods cannot.
• Includes phylogenetically diverse clinical isolates, likely capturing a broad range of strain variation.
• Quantitative analysis of opa variation is supported by developed bioinformatics and phylogenetics tools.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (21.4 KB), indicating it likely contains summary or processed data rather than raw sequence files.

Provenance

Source

figshare

Collection Method

Long-read sequencing of clinical isolates, followed by genome assembly and bioinformatics analysis.

Freshness

Last updated 2026-05-11 17:47:00; freshness should be verified.