Complete miRNA Feature List with Annotations for Pancreatic Cancer Diagnosis

A 20-microRNA signature for pancreatic cancer diagnosis, validated across multiple independent cohorts. The model was developed using 801 samples, including 767 for training and validation, and achieved cross-validation AUCs up to 0.87. Author Yanfei Zhu published this feature list on figshare in May 2026 under a CC-BY-4.0 license.

Use Cases

• Training diagnostic classifiers based on the described 20-miRNA signature.
• Conducting SHAP analysis to interpret feature importance, as referenced in the study.
• Validating miRNA biomarker performance across different platforms like RNA-seq and qRT-PCR.
• Performing functional enrichment analysis on cancer-related pathways mentioned in the results.

Strengths

• Includes a specific 20-miRNA signature identified through feature selection.
• Model was externally validated across independent cohorts, including TCGA-PAAD and GTEx pancreas data.
• Dataset is small (13.0 KB) and in a standard XLSX format for easy inspection.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• Data is based on retrospective studies, as noted in the conclusions.
• The 13.0 KB file size suggests a limited feature list rather than raw expression data.

Provenance

Source

figshare, author Yanfei Zhu.

Collection Method

Feature list derived from model development using public datasets (GSE59856, GSE85589, TCGA-PAAD, GTEx, GSE128508).

Time Range

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Freshness

Last updated 2026-05-04 17:37:37.

Geography

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