Cytokine Concentrations in Mouse Intracerebral Hemorrhage Study

An 11.0 KB Excel dataset contains concentrations of the cytokines TNF-α and IL-6 measured by ELISA. The data originates from a preclinical study assessing the effects of GABAAR modulators on inflammation and neurorestoration in a mouse model of intracerebral hemorrhage. It was authored by Tingting Chen and shared under a CC BY 4.0 license.

Use Cases

• Analyze TNF-α and IL-6 concentration levels to compare inflammatory responses between treatment groups in the ICH mouse model.
• Correlate cytokine levels with histological or behavioral outcomes described in the associated study to validate neuroprotective effects.
• Use the ELISA-measured TNF-α and IL-6 data as a benchmark for inflammation in similar preclinical neuroscience research.

Strengths

• Data is directly linked to a detailed, peer-reviewed preclinical study on intracerebral hemorrhage and neurorestoration.
• Specific focus on two key pro-inflammatory cytokines, TNF-α and IL-6, measured via the standardized ELISA method.
• Shared under a permissive CC BY 4.0 license, facilitating reuse and redistribution.

Limitations

• The dataset is very small at 11.0 KB, indicating limited scope and likely a low number of observations or samples.
• Without access to the sample data or column definitions, the exact structure and granularity of the measurements are unknown.
• Data is confined to a single, controlled animal model study, limiting generalizability to human clinical contexts.

Provenance

Source

Figshare, authored by Tingting Chen.

Collection Method

ELISA measurements of cytokines from a collagenase IV-induced intracerebral hemorrhage mouse model.

Freshness

Last updated on 2026-03-23.