Preliminary Core Outcome Set for Prognostic Impact Studies in Advanced Cancer

9 core outcomes for evaluating prognostic models in advanced cancer, spanning five domains: physiological/clinical outcomes, global quality of life, care delivery, perceived health status, and personal circumstances. The set was developed via a systematic review identifying 70 outcomes, patient interviews adding 16, and a two-round Delphi survey with 49 experts from 14 countries. Caitlin Medlock published the dataset on figshare in April 2026.

Use Cases

• Standardizing outcome selection in clinical trials based on the 9 agreed core outcomes.
• Comparing the impact of different prognostic models based on the five defined outcome domains.
• Informing patient-centered research design based on outcomes identified from interviews with patients and caregivers.

Strengths

• Development followed the Core Outcome Measures in Effectiveness Trials (COMET) initiative's recommended methodology.
• International expert panel of 49 participants from 14 countries contributed to the Delphi survey.
• Outcomes were consolidated from a systematic review of 70 outcomes and patient interviews adding 16 more.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 9.5 KB, indicating limited scope.

Provenance

Source

Caitlin Medlock via figshare.

Collection Method

Systematic review, patient/caregiver/clinician interviews, and a two-round modified Delphi survey with an international expert panel.

Time Range

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Freshness

Last updated 2026-04-09 17:30:58; freshness should be verified.

Geography

Study involved experts from 14 countries.