Pig Model Data on Neuromedin U and Diuresis Under Elevated Left Atrial Pressure

Experimental data from a study investigating neuromedin U (NMU) as a potential biomarker for elevated left atrial pressure in pre-heart failure. The dataset contains results from 8 chloralose-anesthetized female pigs where left atrial pressure was increased above 15 mmHg for 30 minutes. It was authored by Vincent Healy and last updated on 2026-05-08.

Use Cases

• Analyzing the correlation between serum NMU levels and urine flow rate based on the described experimental procedure.
• Investigating the renal effects of increased left atrial pressure based on the reported glomerular filtration rate changes.
• Modeling the role of the vagus nerve in mediating cardiac-renal reflexes based on the post-vagal section results.
• Assessing NMU's potential as a diagnostic biomarker for pre-heart failure based on the study's conclusions.

Strengths

• Data is from a controlled animal experiment with 8 subjects.
• Specific physiological thresholds are reported (pressure >15 mmHg for 30 minutes).
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 18.7 KB, indicating limited scope.

Provenance

Source

figshare, authored by Vincent Healy.

Collection Method

Experimental data collected from 8 chloralose-anesthetized female pigs.

Time Range

The experimental timeframe is not specified.

Freshness

Last updated 2026-05-08 17:25:39; freshness should be verified.

Geography

Geographic origin of the study is not specified.