Data Collection for a Pragmatic Trial on Acute Rhinosinusitis Treatments

Daniel Merenstein's dataset contains outcome measures for a large, multi-center, pragmatic randomized controlled trial evaluating antibiotic and non-antibiotic treatments for acute rhinosinusitis (ARS). The trial, which is placebo-controlled and conducted in U.S. primary and urgent care settings, aims to enroll 3,720 adult participants. The dataset was last updated on May 6, 2026.

Use Cases

• Analyzing symptom severity outcomes based on the modified Sino-Nasal Outcome Test-16 (SNOT-16) scores mentioned in the description.
• Modeling patient subgroups most likely to benefit from specific therapies based on clinical and laboratory indicators described in the trial.
• Comparing the effectiveness of treatment strategies (supportive care, antibiotics, intranasal corticosteroids) as outlined in the trial protocol.

Strengths

• Dataset is associated with a large-scale trial aiming to enroll 3,720 participants.
• Trial design is pragmatic and multi-center, conducted across six U.S. regions, which may enhance generalizability.
• License is CC-BY-4.0, permitting broad reuse with attribution.

Limitations

• Row count is unknown, which may limit suitability assessment for large-scale analysis.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (9.5 KB), indicating it likely contains summary or protocol information rather than individual patient records.

Provenance

Source

Daniel Merenstein via figshare.

Collection Method

Data collected as part of a placebo-controlled randomized clinical trial in primary and urgent care settings.

Time Range

Trial is described as underway; specific dates are not provided.

Freshness

Last updated 2026-05 06 17:29:10; freshness should be verified.

Geography

Six regions across the United States.