Mouse Fibrosarcoma Immune Gene Expression Profiles for Radiation Therapy Research

12 mouse tumors were analyzed for immune-related gene expression profiles, comparing autochthonous tumors induced by 3-methylcholanthrene with transplanted tumors. The dataset includes measurements for genes Pd1, Pdl1, Pdl2, Cd3d, Cd8a, Cd8b, Ifnγ, Itga2, Gzmb, and Foxp3. Author Hiroshi Tanooka deposited the data on figshare under a CC-BY-4.0 license.

Use Cases

• Comparing immune gene expression profiles between autochthonous and transplanted tumors based on the described experimental design.
• Analyzing the relationship between immune cell markers (e.g., DX5+ NK cells, CD8+ T cells) and tumor transplantability based on the findings.
• Investigating the role of specific immune genes (Pd1, Pdl1, Pdl2, Cd3d, Cd8b, Ifnγ) in tumor curability following transplantation.
• Correlating IFNγ expression levels with tumor phenotype (benign vs. transplantable) as described in the study.

Strengths

• Includes expression data for 10 specific immune genes across 12 tumors.
• Provides a direct comparison between autochthonous and transplanted tumor models, a key experimental feature.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.

Provenance

Source

figshare

Collection Method

Experimental analysis of mouse fibrosarcomas induced by 3-methylcholanthrene.

Freshness

Last updated 2026-04-24 17:47:08; freshness should be verified.