Canine Intervertebral Disc Degeneration MTR Measurements from Post-Mortem MRI

181 intervertebral discs from 9 dogs were analyzed using magnetization transfer ratio (MTR) measurements from T2-weighted MRI sequences. This pilot study by Charlène Paquet, published in 2026, correlates MTR values with Pfirrmann grades, Thompson grades, and histological staining to assess disc degeneration. The data suggests MTR could provide a more objective, quantitative tool for diagnosing spinal conditions in chondrodystrophic and non-chondrodystrophic breeds.

Use Cases

• Correlating quantitative MRI metrics with qualitative Pfirrmann grades based on the described methodology.
• Developing models for objective assessment of intervertebral disc degeneration based on magnetization transfer ratio (MTR) values.
• Validating imaging biomarkers against macroscopic and histological evaluations as mentioned in the study.

Strengths

• Includes multi-modal validation with Pfirrmann grades, Thompson grades, and histological staining.
• Data is openly licensed under CC-BY-4.0, permitting reuse and redistribution.
• Study design includes 181 intervertebral discs from both chondrodystrophic and non-chondrodystrophic dog breeds.

Limitations

• Dataset is very small at 2.7 KB; row count and column-level documentation are unknown.
• Data is derived from a pilot study on post-mortem samples; in vivo validation is noted as necessary.
• File format is TXT, which may require parsing to understand the structure of the contained data.

Provenance

Source

figshare, author Charlène Paquet.

Collection Method

MRI acquisitions performed on spinal columns harvested post-mortem, with subsequent grading and measurement.

Time Range

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Freshness

Last updated 2026-04-21 17:23:16.

Geography

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