Murine Model Data on Artemether Effects for Type 1 Diabetes Liver Injury

Artemether administration significantly attenuated diabetic manifestations and liver injury in a murine model of Type 1 diabetes. The dataset likely contains quantitative results from histopathology, transmission electron microscopy, gene/protein expression analysis, and UPLC-QQQ-MS/MS metabolomics. Qike Fu authored this 19.1 KB dataset, last updated on 2026-04-29.

Use Cases

• Analyze the relationship between mitochondrial morphology and liver injury based on ultrastructural examination data.
• Model changes in glucose and lipid metabolic pathways based on quantified metabolic intermediate concentrations.
• Correlate gene/protein expression levels of respiratory chain complexes with hepatoprotective effects.
• Investigate the modulation of hepatic fatty acid β-oxidation and de novo synthesis markers by artemether treatment.

Strengths

• Data integrates multi-modal analysis including histopathology, molecular biology, and metabolomics (UPLC-QQQ-MS/MS).
• The 19.1 KB XLSX file suggests a structured, tabular format for quantitative results.
• License is CC-BY-4.0, permitting broad reuse with attribution.

Limitations

• Row count is unknown, which may limit suitability assessment for statistical analysis.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's scale is limited to 19.1 KB, indicating a focused experimental study rather than a large-scale resource.

Provenance

Source

figshare

Collection Method

Experimental data from a murine model study, with analysis involving histopathology, TEM, molecular assays, and mass spectrometry.

Freshness

Last updated 2026-04-29 17:44:21; freshness should be verified.